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| Standard Gene Set Name | RIDER_UNIUNICONAZOLE-P_PKL_UP |
| Species | Arabidopsis thaliana |
| Brief Description | Up-regulated on exhibit uniconazole-P-dependent and PKL-dependent transcription based on the criteria Wt vs. Upkl p < 0.05 ?? Pkl vs. Upkl p < 0.05 ?? Uwt vs. Upkl p < 0.05) and for which the corresponding transcript level is elevated two-fold or more. (Table S3 PubmedID:12834400) |
| Full Description/Abstract | In angiosperms, germination represents an important developmental transition during which embryonic identity is repressed and vegetative identity emerges. PICKLE (PKL) encodes a CHD3-chromatin remodeling factor necessary for the repression of expression of LEAFY COTYLEDON1 (LEC1), a central regulator of embryogenesis. A candiDate gene approach and microarray analysis identified nine additional genes that exhibit PKL-dependent repression of expression during germination. Transcripts for all three LEAFY COTYLEDON genes, LEC1, LEC2, and FUS3, exhibit PKL-dependent repression, and all three transcripts are elevated more than 100-fold in pkl primary roots that inappropriately express embryonic traits (ˇ°pickle rootsˇ±). Three other genes that exhibit PKL-dependent regulation have expression patterns correlated with zygotic or somatic embryogenesis, and one gene encodes a putative LIM domain transcriptional regulator that is preferentially expressed in siliques. Genes that exhibit PKL-dependent repression during germination are not necessarily regulated by PKL at other points in development. Our Data suggest that PKL selectively regulates a suite of genes during germination to repress embryonic identity. In particular, we propose that PKL acts as a master regulator of the LEAFY COTYLEDON genes, and that joint derepression of these genes is likely to contribute substantially to expression of embryonic identity in pkl seedlings |
| External Pathway ID/Pubmed ID | 12834400 |
| Source | Literature |
| Contributor/Author | Liming Lai and Xijin Ge |
| Organization of contributer | South Dakota State University |
| External URL | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515612/pdf/nihms-58419.pdf |