Detailed Information |
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| Standard Gene Set Name | LUKOWITZ_WT_YDA-2_DN |
| Species | Arabidopsis thaliana |
| Brief Description | Down-regulated gene Expression in Wild-type and yda-2 (Table S2 PubmedID:14718171) |
| Full Description/Abstract | The Arabidopsis zygote divides asymmetrically into an embryonic apical cell and a basal cell with mostly extra-embryonic fate. This fundamental asymmetry sets the stage for further embryonic development, but the events mediating it are poorly understood. We have identified a MAPKK kinase gene, named YODA, that promotes extra-embryonic cell fates in the basal lineage. In loss-of-function mutants, the zygote does not elongate properly, and the cells of the basal lineage are eventually incorporated into the embryo instead of differentiating the extra-embryonic suspensor. Gain-of-function alleles cause exaggerated growth of the suspensor and can suppress embryonic development to a degree where no recognizable proembryo is formed. Our results imply that a MAP kinase cascade acts as a molecular switch promoting extra-embryonic fate |
| External Pathway ID/Pubmed ID | 14718171 |
| Source | Literature |
| Contributor/Author | Liming Lai and Xijin Ge |
| Organization of contributer | South Dakota State University |
| External URL | http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WSN-4BFVD48-H-1&_cdi=7051&_user=10&_orig=search&_coverDate=01%2F09%2F2004&_sk=998839998&view=c&wchp=dGLbVlb-zSkWz&md5=e61e967cde1a04466abc9af293a7c733&ie=/sdarticle.pdf |