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| Standard Gene Set Name | LEEA_WS-2_INOCULATION_TUMOR_DN |
| Species | Arabidopsis thaliana |
| Brief Description | Down- regulated expressed Arabidopsis thaliana (Ws-2) genes _Suppl-Figure 2A: Table lists all genes shown in Figure 2A differentially transcribed in the following experiments: (i) Three hours post inoculation of wounded inflorescence stalks with A. tumefaciens strain C58 (C58 3 hpi) and (ii) with strain GV3101 (GV3101 3 hpi); (iii) six days post inoculation with strain C58 (C58 6 dpi) and (iv) with GV3101 (GV3101 6 dpi), as well as (v) 35 day-old tumors induced by strain C58 (tumor 35 dpi). (DatasetsS 1 PubmedID:19794116) |
| Full Description/Abstract | Agrobacterium tumefaciens causes crown gall disease by transferring and integrating bacterial DNA (T-DNA) into the plant genome. To examine the physiological changes and adaptations during Agrobacterium-induced tumor development, we compared the profiles of salicylic acid (SA), ethylene (ET), jasmonic acid (JA), and auxin (indole-3-acetic acid [IAA]) with changes in the Arabidopsis thaliana transcriptome. Our Data indicate that host responses were much stronger toward the oncogenic strain C58 than to the disarmed strain GV3101 and that auxin acts as a key modulator of the Arabidopsis¨CAgrobacterium interaction. at initiation of infection, elevated levels of IAA and ET were associated with the induction of host genes involved in IAA, but not ET signaling. After T-DNA integration, SA as well as IAA and ET accumulated, but JA did not. This did not correlate with SA-controlled pathogenesis-related gene expression in the host, although high SA levels in mutant plants prevented tumor development, while low levels promoted it. Our Data are consistent with a scenario in which ET and later on SA control virulence of agrobacteria, whereas ET and auxin stimulate neovascularization during tumor formation. We suggest that crosstalk among IAA, ET, and SA balances pathogen defense launched by the host and tumor growth initiated by agrobacteria |
| External Pathway ID/Pubmed ID | 19794116 |
| Source | Literature |
| Contributor/Author | Liming Lai and Xijin Ge |
| Organization of contributer | South Dakota State University |
| External URL | NA |