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| Standard Gene Set Name | GOMEZ-MENA_AGGR-ACTIVATION_UP |
| Species | Arabidopsis thaliana |
| Brief Description | Upregulated 1, 3 and 7 days after AGGR activation (Table S1 PubmedID:15634696) |
| Full Description/Abstract | Floral organs, whose identity is determined by specific combinations of homeotic genes, originate from a group of undifferentiated cells called the floral meristem. In Arabidopsis, the homeotic gene AGAMOUS (AG) terminates meristem activity and promotes development of stamens and carpels. To understand the program of gene expression activated by AG, we followed genome-wide expression during early stamen and carpel development. The AG target genes included most genes for which mutant screens revealed a function downstream of AG. Novel targets were valiDated by in situ hybridisation and binding to AG in vitro and in vivo. Transcription factors formed a large fraction of AG targets, suggesting that during early organogenesis, much of the genetic program is concerned with elaborating gene expression patterns. The results also suggest that AG and other homeotic proteins with which it interacts (SEPALLatA3, APETALA3, PISTILLatA) are coordinately regulated in a positive-feedback loop to maintain their own expression, and that AG activates biosynthesis of gibberellin, which has been proposed to promote the shift from meristem identity to differentiation. |
| External Pathway ID/Pubmed ID | 15634696 |
| Source | Literature |
| Contributor/Author | Liming Lai and Xijin Ge |
| Organization of contributer | South Dakota State University |
| External URL | http://dev.biologists.org/cgi/reprint/132/3/429 |